London rivals meet in the Premier League as West Ham United take on Chelsea at the London Stadium. The Hammers were 1-0 winners when these sides met here last season.
Bayer Leverkusen host Mainz in the Bundesliga at BayArena. Leverkusen are bottom of the table having lost their opening three matches for the first time ever.
Arsenal face Everton at the Emirates Stadium in the Premier League. Arsenal won both meetings between the sides last season.
Eintracht Frankfurt go toe-to-toe with RB Leipzig in the Bundesliga at Commerzbank-Arena. Sebastian Haller is looking to score in his fourth consecutive match for Frankfurt.
Philadelphia Union take on Sporting Kansas City at Talen Energy Stadium in Major League Soccer.
Lyon go toe-to-toe with Marseille in Ligue 1 at the Groupama Stadium. Lyon have a fantastic record against their opponents having lost just once in their last 16 league meetings.